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| Soluble epoxide hydrolase ： ウィキペディア英語版 |
Epoxide hydrolase 2
Soluble epoxide hydrolase (sEH) is a bifunctional enzyme that in humans is encoded by the EPHX2 gene.〔〔〔 sEH is a member of the epoxide hydrolase family. This enzyme, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding diols. A different region of this protein also has lipid-phosphate phosphatase activity. Mutations in the EPHX2 gene have been associated with familial hypercholesterolemia.〔
== Tissue distribution ==
While most highly expressed in the liver, sEH is also expressed in other tissues including vascular endothelium, leukocytes, red blood cells, smooth muscle cells, adipocytes and the kidney proximal tubule.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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